Bovine Alpha Thrombin Purified FPRCK Active Site Blocked Biotin Labeled from Innovative Research has been prepared from purified prothrombin. This is a frozen liquid buffered in 20 mM Hepes, 150 mM NaCl, pH 7.4, with a purity of greater than 95% as determined by SDS-PAGE analysis.
Thrombin (Coagulation Factor IIa) is created by the cleaving of Prothrombin (Coagulation Factor II) by Factor Xa/V during the clotting process. Thrombin acts as a catalyst in various coagulation reactions, including converting fibrinogen into fibrin, activating factors XI, VIII, V, and XIII, and promoting platelet activation/aggregation by activating protease-activated receptors. Thrombin is inactivated by antithrombin.
More Details:
- Source: Bovine Plasma
- Purity: > 95% by SDS-PAGE
- Storage Conditions: -80C
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Please note – this product replaces our old product number IRBAT-BFPRCK (same product, new number).